The restrictions will begin in the 2014-2015 school year and will eliminate foods like candy bars, chips, and pastries during the school day.
Taking their place will be healthier choices such as fruit, granola bars and nuts.
Agriculture Secretary Tom Vlsack says the “Smart Snacks in Schools" program is key to helping with childhood obesity.
"Nothing is more important than the health and well-being of our children," Vilsack noted.
Other rules say snacks will be capped at 200 calories, and entrees will have to come in under 350.
The regulations won’t affect food brought from home or anything sold at any event that takes place after the school day.
"It doesn’t make sense for schools to teach nutrition in the classroom, then counter it by selling sugary drinks and candy bars in vending machines in the hallway," one nutritional counselor said.