The episode first aired in March and featured scenes of a car running over marathon runners as well as a cell phone call triggering a bomb blowing up a bridge.
After the bombings at the Boston Marathon someone performed a mash up to make it look like the phone call triggered the bombs at the marathon.
Fox has pulled the episodes, called Turban Cowboy from the internet and TV and is making an effort to have it removed from YouTube.
Family Guy creator Seth MacFarlane took to Twitter to say "The edited Family Guy clip currently circulating is abhorrent. The event was a crime and a tragedy, and my thoughts are with the victims."
The Los Angeles Times reported that the latest meme on the Internet is that MacFarlane predicted Monday's bombings with the episode.
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