Vatican City - The College of Cardinals took less than two days to choose the new leader of the Catholic Church, naming Argentinian Cardinal Jorge Mario Bergoglio as the 267th Pope.
It's a historic choice, as the church has never had a Pope from the Western Hemisphere.
Pope Gregory III was Syrian born, and was proclaimed Pope by acclamation of the Roman people in the year 731.
He will reportedly take the name of Pope Francis I, another first.
The news began breaking a little after 1:00 p.m. local time in Tulsa, as white smoke billowed from the chimney atop the Sistine Chapel in the Vatican.
A large number of the world's 1.2 billion Catholics live in South America.
A throng estimated at about 100,000 packed St. Peter's Square to hear the announcement and see the new Pope make his first public appearance.
His predecessor, Pope Benedict, was the first Bishop of Rome to step down from that post in nearly 600 years.